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Published Work

Contribution to Science

Publications: Publications

List of Publication

1: Kodama H, Shamay Y, Kimura Y, Shah J, Solomon SB, Heller D, Srimathveeravalli

G. Electroporation-induced changes in tumor vasculature and microenvironment can

promote the delivery and increase the efficacy of sorafenib nanoparticles.

Bioelectrochemistry. 2019 Dec;130:107328. doi: 10.1016/j.bioelechem.2019.107328.

Epub 2019 Jul 6. PubMed PMID: 31306879.

2: Harvey JD, Williams RM, Tully KM, Baker HA, Shamay Y, Heller DA. An in Vivo

Nanosensor Measures Compartmental Doxorubicin Exposure. Nano Lett. 2019 Jul

10;19(7):4343-4354. doi: 10.1021/acs.nanolett.9b00956. Epub 2019 Jun 18. PubMed

PMID: 31244242.

3: Shamay Y, Shah J, Işık M, Mizrachi A, Leibold J, Tschaharganeh DF, Roxbury D,

Budhathoki-Uprety J, Nawaly K, Sugarman JL, Baut E, Neiman MR, Dacek M, Ganesh

KS, Johnson DC, Sridharan R, Chu KL, Rajasekhar VK, Lowe SW, Chodera JD, Heller

DA. Quantitative self-assembly prediction yields targeted nanomedicines. Nat

Mater. 2018 Apr;17(4):361-368. doi: 10.1038/s41563-017-0007-z. Epub 2018 Feb 5.

PubMed PMID: 29403054; PubMed Central PMCID: PMC5930166.

4: Mizrachi A, Shamay Y, Shah J, Brook S, Soong J, Rajasekhar VK, Humm JL, Healey

JH, Powell SN, Baselga J, Heller DA, Haimovitz-Friedman A, Scaltriti M.

Tumour-specific PI3K inhibition via nanoparticle-targeted delivery in head and

neck squamous cell carcinoma. Nat Commun. 2017 Feb 13;8:14292. doi:

10.1038/ncomms14292. PubMed PMID: 28194032; PubMed Central PMCID: PMC5316830.

5: Shamay Y, Elkabets M, Li H, Shah J, Brook S, Wang F, Adler K, Baut E,

Scaltriti M, Jena PV, Gardner EE, Poirier JT, Rudin CM, Baselga J,

Haimovitz-Friedman A, Heller DA. P-selectin is a nanotherapeutic delivery target

in the tumor microenvironment. Sci Transl Med. 2016 Jun 29;8(345):345ra87. doi:

10.1126/scitranslmed.aaf7374. PubMed PMID: 27358497; PubMed Central PMCID:


6: Shamay Y, Golan M, Tyomkin D, David A. Assessing the therapeutic efficacy of

VEGFR-1-targeted polymer drug conjugates in mouse tumor models. J Control

Release. 2016 May 10;229:192-199. doi: 10.1016/j.jconrel.2016.03.024. Epub 2016

Mar 19. PubMed PMID: 27001892.

7: Roxbury D, Jena PV, Shamay Y, Horoszko CP, Heller DA. Cell Membrane Proteins

Modulate the Carbon Nanotube Optical Bandgap via Surface Charge Accumulation. ACS

Nano. 2016 Jan 26;10(1):499-506. doi: 10.1021/acsnano.5b05438. Epub 2015 Dec 11.

PubMed PMID: 26654246; PubMed Central PMCID: PMC4975035.

8: Jena PV, Shamay Y, Shah J, Roxbury D, Paknejad N, Heller DA. Photoluminescent

carbon nanotubes interrogate the permeability of multicellular tumor spheroids.

Carbon N Y. 2016 Feb 1;97:99-109. doi: 10.1016/j.carbon.2015.08.024. PubMed PMID:

26456974; PubMed Central PMCID: PMC4594636.

9: Shamay Y, Raviv L, Golan M, Voronov E, Apte RN, David A. Inhibition of primary

and metastatic tumors in mice by E-selectin-targeted polymer-drug conjugates. J

Control Release. 2015 Nov 10;217:102-12. doi: 10.1016/j.jconrel.2015.08.029. Epub

2015 Aug 18. PubMed PMID: 26297207.

10: Golani-Armon A, Golan M, Shamay Y, Raviv L, David A. DC3-decorated polyplexes

for targeted gene delivery into dendritic cells. Bioconjug Chem. 2015 Feb

18;26(2):213-24. doi: 10.1021/bc500529d. Epub 2015 Feb 9. PubMed PMID: 25560976.

11: Kogan-Zviagin I, Shamay Y, Nissan A, Sella-Tavor O, Golan M, David A.

Intra-colonic administration of a polymer-bound NIRF probe for improved

colorectal cancer detection during colonoscopy. J Control Release. 2014 Oct

28;192:182-91. doi: 10.1016/j.jconrel.2014.06.058. Epub 2014 Jul 6. PubMed PMID:


12: Shamay Y, Shpirt L, Ashkenasy G, David A. Complexation of cell-penetrating

peptide-polymer conjugates with polyanions controls cells uptake of HPMA

copolymers and anti-tumor activity. Pharm Res. 2014 Mar;31(3):768-79. doi:

10.1007/s11095-013-1198-x. Epub 2013 Sep 10. PubMed PMID: 24019024.

13: Journo-Gershfeld G, Kapp D, Shamay Y, Kopeček J, David A. Hyaluronan

oligomers-HPMA copolymer conjugates for targeting paclitaxel to

CD44-overexpressing ovarian carcinoma. Pharm Res. 2012 Apr;29(4):1121-33. doi:

10.1007/s11095-012-0672-1. Epub 2012 Feb 16. PubMed PMID: 22350800.

14: Kopansky E, Shamay Y, David A. Peptide-directed HPMA copolymer-doxorubicin

conjugates as targeted therapeutics for colorectal cancer. J Drug Target. 2011

Dec;19(10):933-43. doi: 10.3109/1061186X.2011.632011. Epub 2011 Nov 10. PubMed

PMID: 22074249.

15: Shamay Y, Adar L, Ashkenasy G, David A. Light induced drug delivery into

cancer cells. Biomaterials. 2011 Feb;32(5):1377-86. doi:

10.1016/j.biomaterials.2010.10.029. Epub 2010 Nov 12. PubMed PMID: 21074848.

16: Shamay Y, Paulin D, Ashkenasy G, David A. Multivalent display of quinic acid

based ligands for targeting E-selectin expressing cells. J Med Chem. 2009 Oct

8;52(19):5906-15. doi: 10.1021/jm900308r. PubMed PMID: 19746918.

17: Shamay Y, Paulin D, Ashkenasy G, David A. E-selectin binding

peptide-polymer-drug conjugates and their selective cytotoxicity against vascular

endothelial cells. Biomaterials. 2009 Nov;30(32):6460-8. doi:

10.1016/j.biomaterials.2009.08.013. Epub 2009 Aug 28. PubMed PMID: 19716600.

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